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With a range of expertly designed applicators for both endometrial and cervical cancer for the female
anatomy, simplified, targeted radiation therapy for gynecological cancer treatment in a minimally shielded
setting is possible with GYN electronic brachytherapy (eBx). Our gynecological applicators provide a
therapeutic dose of radiation therapy for intracavitary treatment of cancer of the uterus, cervix,
endometrium and vagina, while minimizing exposure to surrounding healthy tissue such as the bladder and
rectum.
By providing select gynecological cancer patients with a concentrated dose of electronic brachytherapy
directly to the tumor site, our high dose, low energy technology offers an accelerated course of treatment
as compared to traditional radiation therapy. By streamlining the delivery of care, GYN eBx offers increased
patient compliance and satisfaction.
References
S Lozares, et al. Dosimetric Comparison of Brachytherapy Sources for High Dose-Rate Treatment of
Endometrial Cancer: Electronic Brachytherapy, 192Ir, and 60Co Sources. Presented at AAPM 2017.
S Lozares, et al. Comparison of brachytherapy sources of endometrial cancer: Electronic
brachytherapy source and 192Ir. Presented at ESTRO 2017.
A Villamon, et al. Acute toxicity results after treatment with Xoft Axxent Electronic
Brachytherapy (XB) in patients with endometrial or cervical cancer. Presented at ESTRO 2017.
J Thompson. Feasibility of Cervical Brachytherapy with a Novel 50 kV Electronic Brachytherapy
Source. Presented at RSNA 2014.
M Kamrava, et al. Electronic brachytherapy for postsurgical adjuvant vaginal cuff irradiation
therapy in endometrial and cervical cancer: A retrospective study. Brachytherapy 12 (2013) 141-147.
W Dooley, et al. Use of electronic brachytherapy to deliver postsurgical adjuvant radiation
therapy for endometrial cancer: a retrospective multicenter study. OncoTargets and Therapy 2010:3
197-203.
Dickler, et al. A dosimetric comparison of Xoft Axxent Electronic Brachytherapy and iridium-192
high-dose-rate brachytherapy in the treatment of endometrial cancer. Brachytherapy 2008:5.
A Villamon, et al. Toxicity results after treatment with electronic brachytherapy in patients with
endometrial cancer. Presented at ESTRO37 (2018).
Why eBx?
Targeted
A miniaturized x-ray source delivers a precise dose of radiation directly to the cancerous site.
Convenient
While reducing the number of required treatments, GYN eBx is most often performed as an outpatient procedure, delivered in a minimally shielded setting.
Clinically supported
A growing body of favorable clinical data supports the use of GYN eBx in patients meeting specific selection criteria.1-7
Efficient
Elekta Xoft offers two different angled Colpostat sets to accommodate female anatomy with no radioactive isotopes.
"Elekta Xoft is able to precisely target cancer cells and spare surrounding healthy tissue, resulting in a significant reduction in the radiation dose that reaches organs at risk. Our early results with this targeted technology are very promising, and we are pleased to offer this valuable treatment option to appropriately selected patients with endometrial and cervical cancer.”
Agustina Mendez Villamon Miguel Servet University Hospital, Zaragoza, Spain
Toxicity results after treatment
Toxicity results after treatment with electronic brachytherapy in patients with endometrial cancer8
94 patients
Treated from September 2015 to September 2017
Median follow-up: 11 months
Preliminary results show targeted approach reduces toxicity to organs at risk.
A miniaturized x-ray source delivers a precise dose of radiation directly to the cancerous site. This focused approach carefully destroys cancer cells and spares surrounding healthy tissue.
Specifically designed and wirelessly optimized for surface treatments, the Axxent SPX controller provides physicians with improved flexibility and scalability to treat NMSC lesions in a broader range of treatment environments.
The Axxent extended balloon applicators are a key component of Elekta Xoft, empowering targeted delivery of intracavitary and intraoperative radiation therapy.
The Axxent® vaginal applicators are a key component of the Xoft® Axxent® Electronic Brachytherapy (eBx®) System®, empowering targeted brachytherapy in the vagina and rectum.
The Axxent cervical applicator is a key component of the Xoft® Axxent® Electronic Brachytherapy (eBx®) System®, empowering targeted intracavitary treatment of cancer of the uterus, cervix, endometrium and vagina.
